I really miss Masters of Orion <sniff> and I just wish somebody would bring it back to live again on my iPad. Oh, and M.U.L.E. too. Thank you for listening.
Never played M.U.L.E., but I do like M.O.O. A clone/improvement of Bullfrog's 'Dungeon Keeper II' or 'Syndicate' would be nice as well, if any developers with nothing better to do happen to be reading.
It can't be done. Just look at the UFO/X-COM clone garbage out there. What you want is DOSbox for iPad (work has already started)!
You might want to chekc out the JB forum on this site and the awesome work that's done by litchie in porting dosbox over to the ipad.