Okay I TOFFT'd because I was a big fan of the first.
So when you first start the game, they start a quick test to see how much % of your brain is used, similar to the first game. After the test, you can create your avatar. You can customize his face ranging from his eyes to his beard (For guys), his shirt colour and finally, his hair colour.
Okay you then pick a coach out of the four available, then you can access the main menu. After playing a game for the first time you unlock them in the Training room so you can improve. There are charts to see you improvement which are nothing new. You can also unlock bonus games similar to the first game. There are a few things that are new, Gameloft live is included and how you can create an avatar. There are leaderboards to see who has the highest brain usage too. Of course, there are daily tests which are the core of the game which pick a couple of random games to give you and the results are projected on the charts. There is a brain test, stress tests and a vision test. I believe the vision test is new to the game. And that's about it so far.
There doesn't seem to be anything that is major that was not in the first game with the exception of Gamloft Live, Vision test, creating an avatar and I'm not too sure whether Leaderboards were in the first game (It's been a while since I played the first one) If you liked the first one, I don't see why you shouldn't pick this one up. I believe they are all new minigames.